173 research outputs found
A Realist Argument for the Self: Emotions and Consciousness in Self-Making
The question of the self, of what the self is (or even if there is a self) has been one that has grown alongside humanity, one that has haunted humanity, throughout our collective history. It is the purpose of this study to add to that questioning, and to attempt a small contribution to a field that has been as widely covered as it is perplexing. We will undertake this effort by firstly examining some common and representative accounts of the self and what they pertain, and with that as background we will move into the interdisciplinary areas of psychological and neuroscientific concerns regarding the self. We will discover the central role that emotions and intuition play in self formation and function. Applying those lessons philosophically we will build on our (hopefully achieved) foundation and offer a unique definition of the self. Thereby finding phenomenological matters to be of importance, we will next examine two self accounts from those quarters as possible objections to our own, and too conduct a review of phenomenological methodology. Taking that as guide we will explore consciousness and its relation to the self in some depth before finally proposing a metaphysical manner in which the self on our definition might be judged to be realist. With all of the preceding as grounding we will then analyze time for our self-view and suggest that if one’s self is to be a personal work – a creation – rather than an accident of happenstance then it is out of the perspective on time whence it will come into fruition. Throughout these necessarily broad but deeply interrelated considerations we will strive to maintain a practical approach and limit ourselves only to the human case
Implementation of workflow engine technology to deliver basic clinical decision support functionality
BACKGROUND: Workflow engine technology represents a new class of software with the ability to graphically model step-based knowledge. We present application of this novel technology to the domain of clinical decision support. Successful implementation of decision support within an electronic health record (EHR) remains an unsolved research challenge. Previous research efforts were mostly based on healthcare-specific representation standards and execution engines and did not reach wide adoption. We focus on two challenges in decision support systems: the ability to test decision logic on retrospective data prior prospective deployment and the challenge of user-friendly representation of clinical logic. RESULTS: We present our implementation of a workflow engine technology that addresses the two above-described challenges in delivering clinical decision support. Our system is based on a cross-industry standard of XML (extensible markup language) process definition language (XPDL). The core components of the system are a workflow editor for modeling clinical scenarios and a workflow engine for execution of those scenarios. We demonstrate, with an open-source and publicly available workflow suite, that clinical decision support logic can be executed on retrospective data. The same flowchart-based representation can also function in a prospective mode where the system can be integrated with an EHR system and respond to real-time clinical events. We limit the scope of our implementation to decision support content generation (which can be EHR system vendor independent). We do not focus on supporting complex decision support content delivery mechanisms due to lack of standardization of EHR systems in this area. We present results of our evaluation of the flowchart-based graphical notation as well as architectural evaluation of our implementation using an established evaluation framework for clinical decision support architecture. CONCLUSIONS: We describe an implementation of a free workflow technology software suite (available at http://code.google.com/p/healthflow) and its application in the domain of clinical decision support. Our implementation seamlessly supports clinical logic testing on retrospective data and offers a user-friendly knowledge representation paradigm. With the presented software implementation, we demonstrate that workflow engine technology can provide a decision support platform which evaluates well against an established clinical decision support architecture evaluation framework. Due to cross-industry usage of workflow engine technology, we can expect significant future functionality enhancements that will further improve the technology's capacity to serve as a clinical decision support platform
An ALMA survey of DCN/HCN and DCO/HCO in protoplanetary disks
The deuterium enrichment of molecules is sensitive to their formation
environment. Constraining patterns of deuterium chemistry in protoplanetary
disks is therefore useful for probing how material is inherited or reprocessed
throughout the stages of star and planet formation. We present ALMA
observations at resolution of DCO, HCO, DCN, and
HCN in the full disks around T Tauri stars AS 209 and IM Lup, the
transition disks around T Tauri stars V4046 Sgr and LkCa 15, and the full disks
around Herbig Ae stars MWC 480 and HD 163296. We also present ALMA observations
of HCN in the IM Lup disk. DCN, DCO, and HCO are detected in all
disks, and HCN in all but the IM Lup disk. We find efficient deuterium
fractionation for the sample, with estimates of disk-averaged DCO/HCO
and DCN/HCN abundance ratios ranging from and ,
respectively, which is comparable to values reported for other ISM
environments. The relative distributions of DCN and DCO vary between disks,
suggesting that multiple formation pathways may be needed to explain the
diverse emission morphologies. In addition, gaps and rings observed in both
HCO and DCO emission provide new evidence that DCO bears a
complex relationship with the location of the midplane CO snowline.Comment: 36 pages, 14 figures, updated to match figure order of published
version in Ap
Observed Changes in Risk during Naturopathic Treatment of Hypertension
Few outcome assessments are published from complementary and alternative medicine (CAM) practices. We aimed to describe patient and practice characteristics of ND care for hypertension (HTN), quantify changes in blood pressure (BP), and evaluate the proportion achieving control of HTN during care. A retrospective, observational study of ND practice in HTN was performed in an outpatient clinic in WA State. Eighty-five charts were abstracted for the final analysis. At initiation of care, the mean patient age was 61 years, with 51% having stage 2 HTN, despite common use of anti-hypertensive medications (47%). Patients with both stage 1 and stage 2 HTN appeared to improve during care, with stage 2 patients achieving mean reductions of −26 mmHg (P < .0001) and −11 mmHg (P < .0001) in systolic BP (SBP) and diastolic BP (DBP), respectively. The proportion of patients achieving control (<140/90 mmHg) in both SBP and DBP was increased significantly from 14 to 44% (P < .033), although the statistical significance was not maintained upon correction for multiple comparisons. BP appears to improve during ND care for HTN, in a high-risk population. Randomized trials are warranted
Density currents in the Chicago River : characterization, effects on water quality, and potential sources
Author Posting. © Elsevier B.V., 2008. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Science of The Total Environment 401 (2008): 130-143, doi:10.1016/j.scitotenv.2008.04.011.Bidirectional flows in a river system can occur under stratified flow conditions and in addition to creating significant errors in discharge estimates, the upstream propagating currents are capable of transporting contaminants and affecting water quality. Detailed field observations of bidirectional flows were made in the Chicago River in Chicago, Illinois in the winter of 2005-06. Using multiple acoustic Doppler current profilers simultaneously with a water-quality profiler, the formation of upstream propagating density currents within the Chicago River both as an underflow and an overflow was observed on three occasions. Density differences driving the flow primarily arise from salinity differences between intersecting branches of the Chicago River, whereas water temperature is secondary in the creation of these currents. Deicing salts appear to be the primary source of salinity in the North Branch of the Chicago River, entering the waterway through direct runoff and effluent from a wastewater-treatment plant in a large metropolitan area primarily served by combined sewers. Water-quality assessments of the Chicago River may underestimate (or overestimate) the impairment of the river because standard water-quality monitoring practices do not account for density-driven underflows (or overflows). Chloride concentrations near the riverbed can significantly exceed concentrations at the river surface during underflows indicating that full-depth parameter profiles are necessary for accurate water-quality assessments in urban environments where application of deicing salt is common.The authors greatly appreciate the support provided by USGS, Office of Surface Water (Hydroacoustics Program), the Metropolitan Water Reclamation District of Greater Chicago (MWRDGC), the USGS Illinois Water Science Center
Leveraging Gate-Level Properties to Identify Hardware Timing Channels
Abstract—Modern embedded computing systems such as med-ical devices, airplanes, and automobiles continue to dominate some of the most critical aspects of our lives. In such systems, the movement of information throughout a device must be tightly controlled to prevent violations of privacy or integrity. Unfortunately, bounding the flow of information can often present a significant challenge, as information can flow through channels that are difficult to detect, such as timing channels. As has been demonstrated by recent research in hardware security, information flow tracking techniques deployed at the hardware or gate level show promise at identifying these “timing flows ” but provide no formal statements about this claim nor mechanisms for separating out timing information from other types of flows. In this paper, we first prove that gate-level information flow tracking can in fact detect timing flows. In addition, we work to identify these timing flows separately from other flows by presenting a framework for identifying a different type of flow that we call functional flows. By using this framework to either confirm or rule out the existence of such flows, we leverage the previous work in hardware information flow tracking to effectively isolate timing flows. To show the effectiveness of this model, we demonstrate its usage on three practical examples: a shared bus (I2C), a cache in a MIPS-based processor, and an RSA encryption core, all of which were written in Verilog/VHDL and then simulated in a variety of scenarios. In each scenario, we demonstrate how our framework can be used to identify timing and functional flows and also analyze our model’s overhead
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Cyanide Photochemistry and Nitrogen Fractionation in the Mwc 480 Disk
HCN is a commonly observed molecule in Solar System bodies and in interstellar environments. Its abundance with respect to CN is a proposed tracer of UV exposure. HCN is also frequently used to probe the thermal history of objects, by measuring its degree of nitrogen fractionation. To address the utility of HCN as a probe of disks, we present Atacama Large (sub-) Millimeter Array observations of CN, HCN, H13CN, and HC15N toward the protoplanetary disk around Herbig Ae star MWC 480, and of CN and HCN toward the disk around T Tauri star DM Tau. Emission from all molecules is clearly detected and spatially resolved, including the first detection of HC15N in a disk. Toward MWC 480, CN emission extends radially more than 1'' exterior to the observed cut-off of HCN emission. Quantitative modeling further reveals very different radial abundance profiles for CN and HCN, with best-fit outer cut-off radii of >300 AU and 110 ± 10 AU, respectively. This result is in agreement with model predictions of efficient HCN photodissociation into CN in the outer-part of the disk where the vertical gas and dust column densities are low. No such difference in CN and HCN emission profiles are observed toward DM Tau, suggestive of different photochemical structures in Herbig Ae and T Tauri disks. We use the HCN isotopologue data toward the MWC 480 disk to provide the first measurement of the 14N/15N ratio in a disk. We find a low disk averaged 14N/15N ratio of 200 ± 100, comparable to what is observed in cloud cores and comets, demonstrating interstellar inheritance and/or efficient nitrogen fractionation in this disk.Astronom
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